A move in response to starvation

Human Fibroblast Switches to Anaerobic Metabolic Pathway in Response to Serum Starvation: A Mimic of Warburg Effect

Fibroblasts could be considered as connective tissue cells that are morphologically heterogeneous with diverse functions depending on their location and activity. These cells play critical role in health and disease such as cancer and wound by Production of collagen, fibronectin, cytokines and growth factors. Absence of insulin and other growth factors in serum deprivation condition and similar...

Entosis enables a population response to starvation

Cell death isn’t just about apoptosis anymore. In the last decade, numerous alternative mechanisms have emerged, including regulated forms of necrosis, as well as entosis, a unique mechanism that is executed as a cell murder rather than cell suicide [1]. Hamann et al. now identify glucose starvation as a key inducer of this noncell-autonomous form of cell death [2]. Cells that undergo entosis a...

Zinc starvation response in a cyanobacterium revealed.

The cyanobacterium Anabaena needs a variety of metals for its cellular biochemistry. The general problem is to supply all the different metals to the right enzymes, thereby avoiding toxic side reactions and interference between these metals. Anabaena has to deal with surplus metals but also with metal starvation, and this problem has to be solved for many environments, each with a different ava...

Metabolic response to starvation, injury and sepsis

human fibroblast switches to anaerobic metabolic pathway in response to serum starvation: a mimic of warburg effect

fibroblasts could be considered as connective tissue cells that are morphologically heterogeneous with diverse functions depending on their location and activity. these cells play critical role in health and disease such as cancer and wound by production of collagen, fibronectin, cytokines and growth factors. absence of insulin and other growth factors in serum deprivation condition and similar...